Congratulations to the Institute of Cancer Research Fall 2023 Project Grant Priority Announcement grantees!
The Institute of Cancer Research (ICR) congratulates all the researchers funded through our Fall 2023 Project Grant Priority Announcements! Priority announcements represent additional sources of funding for highly rated applications in the Project Scheme competition that are relevant to ICR's mandate and research priorities.
This competition, ICR supported 28 projects across five Priority Announcements:
Priority Announcement: Early Detection/Cancer Prevention
- Mark Chiew, Sunnybrook Research Institute
Project title: Rapid Diagnostic Imaging of Brain Metastases using Computational MRI - Nathan L DeBono, University of Toronto
Project title: Urinary Phthalate Biomarker Concentrations and Breast and Prostate Cancer Risk in a National Cohort of Adults in Canada - Mathieu Ferron, Institut de recherches cliniques de Montréal
Project title: Role of the vitamin K reductase VKORC1L1 in NAFLD and hepatocellular carcinoma - Joanne Kotsopoulos, Women's College Hospital
Project title: Optimizing Cancer Prediction in Ontario: Leveraging Electronic Medical Records and Machine Learning for Early Detection - Nadia Minian and Scott R Veldhuizen, Centre for Addiction and Mental Health
Project title: Co-creating digital solutions for problem drinking in treatment-seeking smokers to reduce (compounded) risk for cancer - Gregor Reid, University of British Columbia
Project title: Harnessing infection-associated modifiers of paediatric acute lymphoblastic leukaemia progression for therapeutic benefit - Sheila K Singh, McMaster University
Project title: Targeting BACE1 for the prevention and treatment of Brain metastases - Haishan Zeng and Stephen Lam, University of British Columbia
Project title: Advanced Raman Spectroscopy for Exhaled Breath Analysis for Lung Cancer Detection
Priority Announcement: Health Economics and Health Services Research in Cancer Control
- Carrie Ye, University of Alberta
Project title: Gaining Insights Into Immune Checkpoint Inhibitor Associated Inflammatory Arthritis Using Administrative Data
Priority Announcement: Pediatric Cancer Research
- Frédérick A Mallette, CIUSSS Est-de-l'Île-de-Montréal-Maisonneuve Rosemont
Project title: Identifying novel therapeutic vulnerabilities in pediatric acute megakaryoblastic leukemia
Priority Announcement: Cancer Research
- Christine J Allen and Stephanie Lheureux, University of Toronto
Project title: Exploring ATR and PARP Inhibitors for Ovarian Cancer Management: An Innovative Approach - Sharon M Gorski, Simon Fraser University
Project title: Targeting adaptive autophagy to enhance treatment response in pancreatic cancer - Michael F Moran, The Hospital for Sick Children
Project title: Mechanism of cell transformation by aconitase
Priority Announcement: Breast Cancer Research
- Tommy Alain and Tyson Graber, Children's Hospital of Eastern Ontario Research Institute
Project title: Viralyzing transgenes to improve oncolytic immunotherapy - Costin N Antonescu, Toronto Metropolitan University
Project title: Spatial control of PI3K-Akt signaling within clathrin signalosomes - Mark Basik and Terry L Ng, CIUSS de Centre-Ouest-de-l'Île-de-Montréal-Jewish General
Project title: The ESCAPE clinical trial of circulating tumor DNA to guide adjuvant therapy in chemo-resistant triple negative breast cancer - Mark Basik, Saman Maleki and Terry L Ng, CIUSS de Centre-Ouest-de-l'Île-de-Montréal-Jewish General
Project title: Altering the gut microbiome in Triple- negative breast cancer: a pilot study - Andrew Freywald, Nicolas Bisson, Ekaterina Dadachova and Franco J Vizeacoumar, University of Saskatchewan
Project title: Targeting the EGFR/EphA2 crosstalk in triple negative breast cancer - Roger P Leng, University of Alberta
Project title: Role of USP7 and Potential Therapy in Human Cancers - Sheng-Xiang Lin, Université Laval
Project title: Pre-clinical pharmacokinetic and efficacy assays with an efficient 17beta-hydroxysteroid dehydrogenase type 7 inhibitor for breast cancer therapy - Kun Ping Lu, Elizabeth R Gillies, Jakob Magolan and Xiao Zhen Zhou, University of Western Ontario
Project title: Development of Optimized Reversible Pin1 Inhibitors to Block Multiple Cancer-Driving Pathways and to Disrupt Immunosuppressive Tumor Microenvironment - Frédérick A Mallette, CIUSSS Est-de-l'Île-de-Montréal-Maisonneuve Rosemont
Project title: Exploiting translational reprogramming in neoplasia to devise unique strategies to eliminate cancer and cancer-promoting senescent cells - Sylvain Meloche, Université de Montréal
Project title: Role and therapeutic potential of the atypical MAP kinase ERK3 in basal-like breast cancer progression - Roger A Moorehead, University of Guelph
Project title: The role of MXRA8 in breast cancer growth and metastasis - Thomas Moss, Université Laval
Project title: The Ribosomal RNA Genes in Growth, Pluripotency, Senescence and Cancer - Mir Munir Ahmed Rahim, University of Windsor
Project title: Regulation of natural killer cell-mediated immune response in breast cancer - Thomas J Velenosi, University of British Columbia
Project title: Characterizing diacetylspermine as a biomarker of drug response and precision treatment in triple-negative breast cancer - Eldad Zacksenhaus, University Health Network
Project title: Prevention of metastatic triple negative breast cancer (TNBC) by targeting shared- and metastasis-enriched oncogenic pathways
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