Human Immunology Initiative

Deficiencies in the immune system, either genetic or acquired, are key contributors to most chronic conditions and diseases. Our understanding of the immune system and of new preventive and therapeutic approaches is due, in large part, to the use of animal models (mostly mice), however, the animal and human immune systems are often very different. For this reason, it is generally agreed that the translation of immunology research from animals to humans is challenging and that focused studies with the human immune system are required.

Following a number of consultation workshops with collaborating Institutes and the research community, it was concluded that analysis of the human immune system lacks standardization. As such, there is an urgent need to develop and apply standard operating procedures (SOPs) and common approaches for translational research and its application to cohorts in Canada.

The Human Immunology Initiative involves standardization and its application in autoimmune diseases research. It is divided into two distinct funding opportunities:

  1. Standardization Core; and
  2. Human Immunology Research Teams.

The overall goal of this initiative is to create a coordinated workforce in human immunology research and build capacity to develop standardized methods to test novel therapeutic approaches to modulate the immune system in the context of autoimmune diseases.

Contact Centre

For more information on the Initiative contact:

Telephone: 613-954-1968
Toll Free: 1-888-603-4178
Fax: 613-954-1800
support@cihr-irsc.gc.ca

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